Biztalk 2010 - new features

BizTalk Server 2010 introduces enhancements and new features in four main areas:

    * Support for the latest platforms from Microsoft including server, database and development environment.
    * Enhanced developer productivity and new application life cycle management experience for development teams.
    * New capabilities for implementing agile SOA integration solutions across heterogeneous technologies and Line of Business systems.
    * Enhanced B2B and RFID capabilities to allow the implementation of flexible end-to-end supply chain management and asset tracking solutions.

BizTalk Server 2010 introduces enhancements and new features in four main areas:   
    * Support for Visual Studio 2010
    * Support for .NET Framework 4
    * Support for Windows Server 2008 R2
    * Virtualization support with Hyper-V
    * Support for SQL Server 2008 R2  
    * Easy to use BizTalk Data Map and Line-of-Business Connectivity Workflow Foundation (WF) Activities for .NET developers
    * Seamless ability to leverage BizTalk capabilities from SharePoint 2010 Business Connectivity Service to Line-of-Business systems
    * New intuitive & intelligent Data Map and Transformation tools
    * Improved Visual Studio project and wizard-driven tools to build integration solutions with IBM Mainframe and Midrange Systems
    * Built-in components for rapid development of RFID solutions   
    * Single, comprehensive parameter settings dashboard for efficient performance tuning and streamlining deployments across environments
    * New System Center Management Pack to provide enhanced visual monitoring and diagnostics
    * Streamlined setup and live update
    * Support for SQL Server backup compression
    * Support for transparent data encryption   
    * Efficient B2B integration with scalable Trading Partner Management and advanced capabilities for complex data mapping
    * Secure FTP with new FTPS Adapter and an improved FTP Adapter
    * Adapter support for the latest application versions: SAP7, Oracle eBS 12.1, J.D. Edwards 9.0, SQL Server 2008 R2, SharePoint 2010
    * Updated industry protocol adapters
    * Enhancements to the IBM Hosts Systems Adapters


data from: 
http://www.microsoft.com/biztalk/en/us/whats-new.aspx